Trial 100-year-old TB vaccine protects at-risk patients from COVID and may help other infectious diseases

According to a study in the journal Cell Medicine Reports, data from a trial designed to determine whether multiple injections of a tuberculosis vaccine developed in the 1900s can protect diabetes patients from COVID have yielded some positive results.

The trial looked at COVID infection among a group of 144 participants, all of whom had type 1 diabetes, and two-thirds of whom had received at least three doses of BCG, or Bacillus-Calmet-Guérin, which protects people by boosting the immune system. According to the study, the New York Times reported.

The results showed that only 1% of the 96 people who received the BCG injection contracted the disease, compared to 12% of those who received the placebo.

“The BCG group also showed fewer symptoms and severity of infectious diseases and fewer cases of infectious diseases per patient, including COVID-19,” the authors wrote. “There were no systemic adverse events associated with BCG. BCG’s broad-based infection protection may provide that platform protection against new variants of SARS-CoV-2 and other pathogens.

BCG injections are still given to babies in parts of the world where there are cases of TB.

Watch now: CDC: You must have two negative tests or wear a mask for 10 days after testing positive for COVID-19

The movement is easing with known cases of COVID in the U.S., but given how many people are being tested at home, where data is not being collected, the true number could be higher.

The daily average of new cases on Tuesday was 100,747, down 18% from two weeks ago, according to a New York Times tracker. Jobs fell in nearly every state, with more than a dozen states, including Rhode Island, Florida, Nebraska, Connecticut, New York, New Mexico, California, Colorado, New Jersey, Idaho, Kansas, and Louisiana, down 20% or more. decreased. South Carolina, Arkansas, Arizona, Wyoming, Hawaii, Alabama, Utah, Oregon and Illinois.

The daily average of hospitalizations fell by 45 to 41,668, while the daily average of deaths rose 4% to 467.

The head of the Centers for Disease Control and Prevention on Wednesday called for an overhaul of the agency’s handling of the coronavirus pandemic, describing the guidelines for the public as “confusing and overwhelming,” the New York Times reported, citing a briefing document. received.

Dr. According to Rochelle Walensky, the CDC needs a structure that prioritizes public health needs and efforts to prevent current outbreaks and is less focused on publishing scientific papers about rare diseases.

“For 75 years, the CDC and public health have been preparing for Covid-19, and in our biggest moment, our performance has not been as expected,” said Dr. – said Valensky. “My goal is a new, public health, action-oriented culture at CDC that emphasizes accountability, collaboration, communication and timeliness.”

On Monday, Walensky told the newspaper that he encouraged CDC officials to change the COVID data as soon as possible. “Some data is messy and some data takes time,” he said. “When we had the data, I really tried hard to get it out.”

News about the coronavirus: MarketWatch’s daily roundup has updated and reported on the latest developments every day since the start of the coronavirus pandemic

Other COVID-19 news you need to know:

• A record number of people aged 50 and over in the UK have left their jobs earlier than previously expected, the Guardian reported, citing data from the Office for National Statistics. The ONS found that around 77% of adults in this age group said they had quit early, with many saying the pandemic played a role in their decision.

• A California church that defined safety rules for holding large religious services during the COVID-19 pandemic will not have to pay a $200,000 fine after a state appeals court ruled, the Associated Press reported. Calvary Chapel San Jose and its pastors were held in contempt of court and fined for violating state and county restrictions in 2020 and 2021.

China’s economy has stalled, protests have erupted over frozen bank accounts and mortgage payments on unfinished homes. The WSJ explains the reasons for the simmering discontent and how the Beijing authorities are trying to cover it up. Photo credit: WSJ

• The Little League World Series is back after a two-year hiatus caused by the pandemic, the AP reported. The youth baseball tournament begins Wednesday in South Williamsport, Pa. This year’s series marks the 75th anniversary of the first tournament to become a major summer tournament in central Pennsylvania.

• Chaos broke out at an Ikea store in Shanghai over the weekend, the New York Post reports. Videos author Fang Shimin shared online and others showed shoppers fleeing the store before authorities closed the doors on Saturday. The rush to get out came at an Ikea store after authorities said the store was closed and no one would be allowed in or out.

Here’s what the numbers say

The global number of confirmed cases of COVID-19 exceeded 592.5 million on Tuesday, while the death toll exceeded 6.44 million, according to Johns Hopkins University.

The US leads the world with 93.2 million cases and 1,038,039 deaths.

A tracker from the Centers for Disease Control and Prevention shows that 223.5 million people living in the US are fully vaccinated, which is 67.3% of the total population. However, only 107.9 million people are 48.3% of the vaccinated population.

Among people age 50 and older, 21 million had a second sponsor, equal to 32.7% of those who received a first booster.


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