After surgery, some cancer patients may avoid treatment, such as radiation. chemotherapyIn short, two recent studies that examined mild, mild cancer care.
Researchers are looking for ways to predict that cancer patients will avoid unnecessary treatment to reduce costs and side effects.
In one new study, patients with colon cancer used a blood test to see if they could skip chemotherapy after surgery. According to another study, some patients with malignant breast cancer may not need radiation after a surgery called lumpectomy.
The study was recently discussed at the annual meeting of the American Society of Clinical Oncology (ASCO). A study on colon cancer, funded by the Australian and U.S. governments and nonprofits, was recently published by the New England Journal of Medicine.
Research allows physicians to pay close attention to “patients we really think about.” profit Avoid chemotherapy and avoid side effects for patients who do not need it, “said Dr. Fred Hutchinson of the Oncology Center, Stacey Cohen. Cohen did not review the results of colon cancer and did not participate in the study.
Colon cancer research
Although many patients with colon cancer are cured, chemotherapy is given after surgery. The drug can come with side effects like dizziness, anemia and memory problems.
However, it was difficult to determine which patients did not need further treatment. Researchers have examined blood tests to see if they can help doctors make informed decisions.
The study involved 455 patients who underwent surgery for cancer that had spread to the colon wall. After the operation, he received a special blood test tumors Genetic information to find the remaining bits of cancer DNA.
Their care was guided by a blood test. If the test does not show any other signs of cancer, the patients have not received chemotherapy. At the same time, doctors decided to prescribe chemotherapy for the remaining patients in the usual way, guided by a thorough examination of the tumor and nearby tissues.
Fewer patients in the blood test group received chemotherapy – 15 percent compared to 28 percent. However, about 93 percent of both groups recovered from cancer two years later. In other words, the blood test group did equally well with less chemotherapy.
Dr. The study was led by Jeanne Tie of the Peter McCallum Cancer Center in Melbourne, Australia. The results were characterized by recurrence of cancer – recurrence of cancer after a period of improvement.
“In patients without cancer DNA identified “After surgery, the chances of cancer recurring are very low, and this chemotherapy is unlikely to benefit these patients.”
ASCO Presidents Dr. According to Everett Vox, not undergoing chemotherapy “can make a big difference in a person’s quality of life if there is a risk of recurrence.”
Another study followed 500 older women with low levels of a protein called Ki67, a common form of early-stage breast cancer and a sign of rapid-growing cancer.
After the operation, the women took over hormone-Blocking pills are a common treatment for this type of cancer. However, the women were not treated for radiation.
Five years later, 10 women were diagnosed with recurrence of breast cancer, and one died of breast cancer. There were no comparison groups in the study, but the researchers said the results were well compared with historical data for similar patients who had been exposed to radiation.
Dr. The study was led by Timothy Whelan of McMaster University in Hamilton, Ontario.
“We believe that the benefits of radiation will be very small in this population compared to the negative effects,” Whelan said.
Radiation can cause skin problems, fatigue and often long-term heart problems and secondary cancer.
Dr. Deborah Axelrod did not participate in the Langone Health study at New York University.
Axelrod described the study as a “feel good” statement for patients with low-risk tumors. Axelrod added that this information will help doctors understand which of their patients can be “reliably and comfortably” irradiated.
I’m John Russell.
Carla K. Johnson told the Associated Press about the incident. John Russell adapted it for VOA Learning English.
The words in this story
chemotherapy – do not. medical: The use of chemicals to treat or control disease (such as cancer)
profit– v. to be useful or helpful (to someone or something)
dizziness – do not. The feeling inside you when you think of vomiting
anemia – do not. medical: The person has fewer red blood cells than normal and is in a very weak and tired state
tumor – do not. Tissue mass in the body or consisting of abnormal cells
hormone – do not. A natural substance produced in the body and affecting the growth or development of the body
to determine – v. Finding or noticing that there is (hidden or difficult to see, hear, taste, etc.).