Regular consumption of blueberry can reduce the risk of mental disorders

Summary: According to a new study, middle-aged people who eat blueberries every day have a lower risk of developing dementia.

A source: University of Cincinnati

An old proverb says that one apple a day kills a doctor, but new research from the University of Cincinnati shows the potential health benefits of other fruits.

Researchers led by UC Robert Cricorian found that adding blueberries to the daily diet of some middle-aged populations may reduce the chances of developing late-life dementia.

The results were recently published in a magazine nutrients.

Research method

According to Cricorian, his team has been researching the benefits of fruits for people with Alzheimer’s disease and dementia for several years.

Although not at all different from other fruits and plants such as red cabbage, Cricorian said that blueberries have exceptionally high levels of trace elements and antioxidants called anthocyanins. Anthocyanins help blueberries give their color, as well as protect plants from the effects of excessive radiation, infectious agents and other hazards, Cricorian said.

The same properties that help blueberries survive are also beneficial to humans, says Cricorian, reducing inflammation, improving metabolism and increasing energy production in cells.

Previous fruit and vegetable studies have focused on older populations of Cricorian, but with this study, the team wanted to study middle-aged people to prevent dementia and reduce risk.

Cricorian explained that about 50% of people in the United States are resistant to middle-aged insulin, commonly referred to as prediabetes. Prediabetes has been shown to be a factor in chronic diseases, he said.

“In our previous studies with older people, we observed the cognitive benefits of blueberries and thought they could be effective in young people who are intolerant to insulin,” said Kricorian, professor and director of the Department of Psychiatry and Psychology at UC Medical College. Behavioral Neuroscience.

“Alzheimer’s disease, like all chronic diseases of old age, develops over many years from middle age.”

Research details and results

Researchers in Cincinnati registered 33 patients aged 50-65 years who were overweight, diabetic, and had a slight memory loss as they got older. According to Krikorian, this population is at high risk for late-onset dementia and other general conditions.

For 12 weeks, patients were asked to refrain from consuming fruits mixed with water and excluding the daily packet of extra powder for breakfast or dinner. Half of the participants received one and a half cups of powder equal to the whole blueberry, and the other half received a placebo.

Participants were also given tests that measured some of the cognitive abilities of patients with aging and late dementia, such as performance memory, mental flexibility, and self-management.

According to Cricorian, members of the blueberry-treated group showed improvements in cognitive functions that depend on executive control.

“It was clear that third-party information interference during reading and memory was reduced,” Kricorian explained.

According to Cricorian, members of the blueberry-treated group showed improvements in cognitive functions that depend on executive control. Image in public domain

Patients in the blue wolf group had lower fasting insulin levels, which means that participants had improved metabolic function and were able to burn fat more easily for energy.

The Krikorian blue wolf group showed an additional mild degree of greater mitochondrial detachment, a cellular process associated with longer life and reduced oxidative stress. Oxidative stress can lead to symptoms such as fatigue and memory loss.

“It was an exploration of the latest findings, but it shows an interesting, potential mechanism of blueberry benefits,” he said.

Moving forward, Kricorian said he was interested in better understanding the precise mechanisms of blueberries that help improve cognitive ability and metabolic function. However, the main finding of the current study is that regular blueberry supplementation in the diet of middle-aged people at risk may reduce the chances of developing late-term dementia.

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“The size of the lesion is a clear limitation of the study, so it will be important to republish these findings, especially by other researchers,” Cricorian said. “At the same time, it may be a good idea to eat blue wolves on a regular basis.”

This is about diet and dementia research news

Author: Press service
A source: University of Cincinnati
The connection: Press Service – University of Cincinnati
Photo: Image in public domain

Original study: Open access.
“Middle-aged Blueberry Supplement to Reduce the Risk of Dementia” by Robert Krikorian et al. nutrients


Abstract

Middle-aged Blueberry supplement to reduce the risk of dementia

Dementia at a young age usually develops over many years from middle age. The prevalence of metabolic disorders also accelerates in middle age and is a major risk factor for dementia.

Preliminary studies show that blueberry supplementation can improve cognitive performance and affect metabolism and brain function, and therefore plays a role in early intervention to prevent neurodegeneration. In a randomized controlled trial, we examined the effects of daily blueberry supplementation in middle-aged specimens of insulin-resistant participants with a higher risk of future dementia.

We registered overweight men and women aged 50 to 65 years with subjective cognitive impairment (SCD) and conducted a preliminary and follow-up assessment of cognitive and metabolic and peripheral mitochondrial function interventions.

We improved the observed indicators for the Blueberry group on lexical access measures, P = 0.003 and memory interference, P = 0.04, and participants treated with blueberries reported reduced memory coding difficulty in daily life, P = 0.03.

The group treated with blueberry also showed correction of peripheral hyperinsulinemia, P = 0.04 and a simple trend of increasing mitochondrial separation, P = 0.11. Cognitive results showed an improvement in this middle-aged model’s performance. In addition, changes in metabolism and bioenergy measures represent potential mechanical factors associated with the action of anthocyanins and proanthocyanidins.

Demonstration of these benefits in insulin resistance and middle-aged people with SCD suggests that ongoing blueberry supplements may contribute to protection against cognitive decline when administered early in at-risk individuals.

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