Neurofeedback Shows Promise for Addressing the “Chemical Brain.”

Summary: Neurofeedback has the potential to alleviate signs of chemotherapy-related “mind fog” and cognitive impairment.

A supply: UCLA

Restoring regular mind operate in most cancers sufferers by means of neurofeedback could scale back the psychological fogginess many individuals report after therapy, in response to a brand new pilot examine by UCLA researchers.

The examine is the first to indicate that neurofeedback, or electroencephalogram (EEG) biofeedback, will help tackle cognitive deficits in most cancers sufferers with a myriad of signs that may embrace reminiscence, focus, and organizational issues. different signs akin to sleep and emotional difficulties.

Previous research have discovered that neurofeedback, wherein mind waves are skilled to function in optimum frequency patterns, will help enhance cognitive operate and regulate mind exercise in sufferers with cognitive problems akin to consideration deficit/hyperactivity dysfunction, stroke, and epilepsy. Patients with substance abuse and post-traumatic stress problems.

“The historical past of neurofeedback reveals that it’s helpful for many ailments and signs. This examine was a chance to see if neurofeedback will help the chemical mind,” mentioned Steven Sideroff, a professor in UCLA’s Department of Psychiatry and Biobehavioral Sciences who led the examine and has used neurofeedback coaching with sufferers for greater than 20 years.

The examine was revealed this month Journal of Complementary and Integrative Medicine.

The examine, performed by Sideroff and UCLA colleagues David Welsh and Valerie Yarema, included 9 girls with breast most cancers, ages 21 to 65, who had accomplished chemotherapy a minimum of a 12 months earlier and complained of debilitating chemotherapy signs that considerably interfered with their work. private life.

A scientific nurse practitioner performed a short psychological standing interview with every affected person to verify whether or not they had persistent difficulties with focus, reminiscence, group, and confusion.

Patients chosen for the examine didn’t have a present prognosis of breast most cancers, a present or current prognosis of main depressive dysfunction, or different psychological sickness, or weren’t utilizing cognitive-altering medicines that would confound the examine outcomes.

Before neurofeedback coaching, examine contributors acquired neurocognitive and psychological exams, in addition to quantitative EEG to measure mind wave frequency that may very well be in contrast with normative information. Quantitative EEGs earlier than coaching confirmed irregular mind exercise in every examine participant in comparison with a wholesome grownup mind.

Study contributors acquired a collection of 18 neurofeedback classes scheduled for half-hour every over six weeks. During these classes, sensors are positioned on the scalp and earlobes to watch mind wave frequency.

Patients had been proven a monitor that displayed these frequencies in bar graphs and informed that their purpose was to extend or lower the amplitude of particular frequency ranges with a purpose to flip every bar inexperienced. They acquired audio and visible suggestions once they efficiently switched these amplitudes.

Quantitative EEGs taken after the 18 neurofeedback classes confirmed important normalization of mind wave frequency in seven of the 9 examine contributors, and important enchancment in the different two.

Each improved in every day functioning and general psychological well-being. Image is in the public area

Neurocognitive testing performed after neurofeedback classes confirmed important enhancements in examine contributors’ info processing, govt set switching, and sustained visible consideration. Each improved in every day functioning and general psychological well-being.

Study limitations embrace a small pattern dimension and lack of a management group. Another limitation is the prolonged window, which required most examine contributors to endure all 18 neurofeedback classes. Three accomplished their research in the deliberate six-week window, whereas most took seven to 9 weeks. Previous analysis on neurofeedback has discovered that remedy is more practical if classes are held shut collectively.

“Our outcomes had been extra spectacular as a result of we weren’t capable of preserve lessons on schedule,” Sideroff mentioned.

Sideroff mentioned the outcomes of the examine had been adequate to help analysis into whether or not neurofeedback is an efficient methodology in addressing mind chemotherapy and to establish supreme protocols for conducting neurofeedback coaching classes.

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This is about neurotech and most cancers analysis information

Author: Press service
A supply: UCLA
The connection: Press Office – UCLA
Photo: Image is in the public area

Original analysis: Closed entry.
“A neurotherapeutic protocol for reversing cognitive deficits after adjuvant chemotherapy: a pilot examine” by Stephen Sideroff et al. Journal of Complementary and Integrative Medicine


A neurotherapeutic protocol to reverse cognitive deficits after adjuvant chemotherapy: a pilot examine

Adjuvant chemotherapy for breast most cancers is undeniably efficient in enhancing survival, however many breast most cancers survivors (BCS) expertise unwanted side effects, together with nausea, fatigue, stress, and neurocognitive deficits, often known as “chemo-brain.”


This pilot examine investigated how neurotherapy, or EEG biofeedback, a non-pharmacological strategy, improved neurocognitive habits and neurophysiological deficits in BCS present process chemotherapy.


Subjects had 18 profitable classes of EEG suggestions coaching and visible suggestions with audio displacement of EEG patterns.


Quantitative EEG and evaluation exams confirmed neurophysiological, cognitive, and behavioral deficits in all 9 topics previous to coaching. EEG biofeedback resulted in important enhancements in neurophysiological, neurocognitive, and psychological capabilities of all 9 topics after coaching.


We recommend that this intervention and EEG biofeedback-related varieties have the potential to considerably alleviate the widespread unwanted side effects of chemotherapy in BCS and due to this fact warrant additional analysis consideration.

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