Is Covid 19 responsible for the outbreak of hepatitis in children in the UK?

Hundreds of liver health experts gathered at the World Hepatitis Summit last week, and one topic dominated the agenda: the mysterious epidemic of hepatitis in children has gradually spread to 34 countries, including the United Kingdom.

Speaking at the event, Dr. Philip Easterbrook, a liver expert, said: “This is the first time that these children have had such a difficult time. It is important to understand the reasons for this and take it seriously. ‘

Hepatitis can cause severe liver failure. There have been more than 240 reported cases in the UK so far, and 11 British children are in need of transplants.

There may be a topic behind this that divides the scientific world. But the latest news comes from an interesting study by Israeli scientists who say the answer may be with Kovid-19.

Hundreds of liver health experts gathered at the World Hepatitis Summit last week, and one topic dominated the agenda: the mysterious outbreak of pediatric hepatitis has gradually spread to 34 countries, including the United Kingdom.

Some experts have suggested that there may be a link between the mysterious epidemic and Covid 19

Some experts have suggested that there may be a link between the mysterious epidemic and Covid 19

Doctors analyzed the history of five children with dangerous liver inflammation.

They noticed a common factor: everyone arrested Covid last year. According to them, inflammation of the liver can have a very negative effect on the immune system’s response to the virus.

Influential doctors shared on Twitter the news of the invention of the “long Covid liver” phenomenon. Dr Dipti Gurdasani, a British epidemiologist at Queen Mary University in London, took to Twitter to express his confidence in the findings, accusing those who denied them of “denying Covey’s harm to children”. However, many reputable pediatric health experts and epidemiologists have been outraged by these claims.

Professor Alasdair Munro, a pediatric infectious disease expert at the University of Southampton Hospital, said the study “provided almost no useful information” and that there was no evidence that these hepatitis cases were related to Covid.

Dr. Jake Dunning, an infectious disease specialist at Oxford University, said scientists “really need to know better” about Covid’s chronic liver disease.

The theory is that a negative strain of childhood infection called adenovirus predominates – three-quarters of children admitted to British hospitals are positive about this option.

Most children become infected at some point, but it often causes minor upper respiratory problems, including cough, runny nose, and, rarely, pneumonia.

However, experts say that the lack of exposure to adenoviruses during Covid’s lockout has left children’s immune systems unprotected to fight it, leading to a severe reaction. However, the new claims may be a source of concern for parents, so can they be justified?

At first glance, Israel’s research seems plausible. The report, published in the Journal of Pediatric Gastroenterology And Nutrition, describes five patients: two three-year-olds in need of a liver transplant and two eight-year-olds and a 13-year-old boy who were hospitalized but fully recovered. All five were infected with Covid within four months of being diagnosed with hepatitis.

According to the authors, as a result, Covid infection caused the immune system to malfunction and began to attack the liver. It is not found in other viral infections and is known as viral hepatitis in children.

According to Dr. Gurdasani, a vocal advocate of the Long Covey Liver Theory, another piece of evidence is that the United Kingdom and the United States have the highest incidence of hepatitis. Unlike many other nations that use strict Covid-safety measures in schools, both children had very high rates of infection.

“The UK was different from how we tried to protect children from the virus,” says Dr. Gurdasani. “Unlike other countries, we did not require wearing masks and did nothing to ventilate schools. Perhaps we are seeing the impact of those decisions.

The study also casts doubt on another possible cause: no adenovirus was detected in any of the five patients. And this is not the only study that has reached this conclusion. In late April, Alabama doctors published a study showing that nine children with severe hepatitis requiring a transplant were free of the virus.

Many scientists have noted that adenovirus has never been associated with hepatitis before – in fact, no cases of adenovirus hepatitis have been reported in the medical literature. “The argument that adenovirus is the cause is getting weaker,” said Dr. Gurdasani. “It does not cause hepatitis, and many studies have not found it in the livers of these children. Where is the evidence? ”

But experts say there are many problems with the Israeli study. The eldest is only five children.

Twelve children have been diagnosed with hepatitis in Israel, and the study covers less than half of these patients.

“Researchers do not explain why these patients were selected or why other cases of hepatitis were not selected,” says Professor Munro. “We don’t know if they only selected patients with Covid, so that doesn’t mean that the child who raised Covid may have hepatitis.”

According to Professor Munro, Covid is so prevalent that it is not surprising that these children have Covid infection. “Covid infection is very common and there is no clear evidence that these children are infected with the virus and the time between hepatitis is so different that one does not infect the other. This does not mean that there is no specific link between Covid and hepatitis, but does not give.

Professor Will Irving, a virologist at the University of Nottingham, said it was too early to draw conclusions. He says: “Five cases are not enough to prove anything. We have seen how many hundreds of cases in the UK have been in Covey and we have to leave.”

To add to the confusion, U.S. health officials said last week that there were more than 270 cases of unexplained hepatitis in children in the country this year, but not more than usual. “The background to these unexplained cases was before Covey,” says Professor Irving.

One thing that all experts agree on is that finding the cause remains a topical issue because it helps doctors know what treatment to give. In the UK, children hospitalized with hepatitis are treated with adenovirus – the antiviral drug cidofovir. But other countries, such as Israel and Austria, are treating them with steroids, which help regulate the immune system that is affected by Covid.

Dr Gurdasani warns: “If the adenovirus theory is wrong, we have been giving patients the wrong treatment for months. Health professionals in the UK need to pay attention to Covid’s theory if they want to protect children.

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