A 20-year study in Sweden discovered that the “Mediterranean diet” didn’t reduce the risk of dementia.
Previous analysis on the potential cognitive advantages of the so-called Mediterranean diet—broadly outlined as a diet wealthy in greens, fruits, fish, and unsaturated fat comparable to olive oil—and low in dairy, pink meat, and saturated fats. – in accordance to the National Institutes of Health’s National Institute on Aging (NIA), has produced blended outcomes.
However, two 2019 research in the journal JAMA Observations spanning hundreds of individuals and many years recommend that the Mediterranean diet reduces dementia risk or that diet high quality impacts dementia risk on the whole.
A new Swedish study additional casts doubt on the diet’s brain-boosting advantages.
“We discovered no affiliation between common consuming habits or adherence to a Mediterranean diet and subsequent dementia,” mentioned first creator Dr. Isabel Glans, a member of the Department of Clinical Memory Research at Lund University in Sweden, mentioned in an e-mail to Live Science.
The findings, that are in step with earlier research of related dimension and size, had been revealed in the journal Oct. 12. neurology.
Like many earlier research, the study relied on individuals’ dietary information, which can be imprecise and considerably skew the interpretation of the outcomes.
Related: Brain ‘pacemaker’ in Alzheimer’s slows decline
Effects of diet on dementia
Physiologist Ansel Keys and biochemist Margaret Keys, a husband-and-wife duo, derived the Mediterranean diet from Ansel’s analysis on the relationship between males’s diets and their risk of coronary heart assault and stroke.
Research has proven that diets low in saturated fats shield in opposition to heart problems, and Ansel and Margaret drew inspiration from Greek, Italian and different Mediterranean cuisines to write their widespread diet books, The Conversation stories.
In idea, by stopping heart problems, the Mediterranean diet might not directly reduce the risk of dementia, the NIA stories.
This is as a result of plaque in the arteries (atherosclerosis), stroke, hypertension, excessive blood sugar and diabetes all enhance the risk of dementia, and a wholesome diet may help reduce the risk of these situations.
The Swedish study doesn’t utterly disprove this concept, but it surely does recommend that diet alone doesn’t have a noticeable impact on cognitive perform later in life.
“Diet might not have a sturdy sufficient impact on cognition as a singular issue, however could also be seen as a mixture of numerous different elements that might affect cognitive perform.” Nils Peters, MD, a neurologist at the Clinical Hirslanden Stroke Center in Zurich, Switzerland, and Benedetta Nachmias, an affiliate professor of neurology at the University of Florence, wrote in an Oct. 12 commentary. neurology.
These different elements embody common train; keep away from tuxedos; drink solely moderately; and sustaining blood strain, they wrote. In specific, proof shows that common bodily exercise and constant blood strain management are protecting in opposition to cognitive decline, and these elements are in all probability extra influential than diet, in accordance to the NIA.
The new study included information from about 28,000 individuals who participated in the Malmö Diet and Cancer Study, which started in Malmö, Sweden, in the Nineteen Nineties.
Participants had been on common 58 years previous at the begin of the study; At that time, they offered dietary info in the kind of a weekly meals diary; a full questionnaire about the frequency and quantity of consuming totally different meals; and a dialog about their consuming habits.
Based on this info, the analysis staff assigned every participant a rating primarily based on how carefully they adhered to normal Swedish dietary suggestions or a particular model of the Mediterranean diet.
Related: Major study on Mediterranean diet debunked. But do medical doctors nonetheless suggest it?
Over the subsequent 20 years, 1,943 individuals, or 6.9 % of the individuals, had been recognized with some kind of dementia. These diagnoses included the two most typical sorts of dementia: dementia associated to Alzheimer’s illness (AD) and vascular dementia brought on by poor blood circulation to the mind.
The researchers discovered that individuals who adopted both a standard diet or a Mediterranean diet had been no much less probably to develop any kind of dementia than individuals who didn’t comply with both. They additionally discovered a hyperlink between diet and a particular marker of Alzheimer’s illness, which they examined in about 740 individuals with cognitive decline.
Overall, the study “doesn’t point out a particular impact of diet on cognitive perform,” Peters and Nakmias wrote. But like earlier related research, the work has limitations, they famous.
For instance, baseline dietary info collected from every participant might not replicate how their diet has modified over time. Furthermore, study individuals might have barely misreported their precise consuming habits.
The finest method to check the long-term results of the Mediterranean diet on cognition can be to conduct a long-term randomized managed trial. In such a trial, teams of individuals are requested to comply with particular diet plans, and even all of their meals, over a lengthy interval of time and are monitored for indicators of dementia all through.
“However, it isn’t potential to design a 20-year randomized managed trial,” the study authors wrote of their report.
Some short-term trials of this sort may be discovered on the NIA web site and the Alzheimers.gov Clinical Trials Finder. However, up to now, the obtainable proof suggests that the Mediterranean diet is just not a silver bullet for dementia prevention.
Similar content material:
This article was initially revealed by Live Science. We invite you to learn the first article right here.