- Time-restricted eating is a form of intermittent fasting that some believe has metabolic benefits.
- Animal studies of time-restricted feeding have shown that weight loss and reproduction are difficult in humans that show reduced blood glucose.
- However, a recent small study showed that time-restricted eating can have a positive effect on overweight elderly people with type 2 diabetes.
Whether or not eating at a fixed time window each day has any metabolic benefits is a question researchers have been asking in recent years.
Known as time-restricted eating, which is a form of intermittent fasting, animal and human studies have shown significant benefits of this practice, including improved blood glucose and weight loss.
People with type 2 diabetes may benefit from time-restricted eating, as weight loss and lowering blood sugar can help reduce the risk of complications, researchers say.
Now, a small study in the Netherlands of 14 overweight and obese type 2 diabetics showed that a 10-hour time-restricted eating window improved the amount of time spent in a healthy glycemic range and reduced fasting glucose compared to 14. Clockwork window.
The results of the study were published in the journal Diabetologia.
Type 2 diabetes is a form of diabetes in which cells in the body become resistant to the hormone insulin, which normally helps transport glucose, a type of sugar, from the blood into the cells for energy.
People with type 2 diabetes have fewer cells. As blood sugar levels rise, the body cannot adequately compensate for insulin activity. This increase in blood sugar can lead to many complications, including cardiovascular disease and nerve damage.
The number of people with type 2 diabetes has almost quadrupled in less than 40 years and is around
Losing weight can help reduce insulin resistance, and improving blood sugar levels through diet can reduce the risks associated with type 2 diabetes.
Although some studies have shown that time-restricted eating can help with weight loss, its effect on blood sugar in patients with type 2 diabetes is less favorable.
So far, researchers have studied restricted eating windows of up to 6 hours, but generally speaking, the shorter the eating window and the longer the fast, the more difficult it is for people to adhere and the less likely they are to adhere.
Dr. Lucy Chambers, Head of Research Communications, Diabetes UK Medical news today:
“It’s important to remember that there is no one-size-fits-all diet for type 2 diabetes, and the best diet is the one you stick to. If you are living with type 2 diabetes and trying to lose weight, getting the right support is also very important.”
One of the reasons researchers think time-restricted eating helps improve metabolism is because humans (and other animals) are adapted to fast during their daily rest or sleep phase. The demands of modern life, including shift work and increased food intake, have compromised our metabolism, making it less likely that we will miss this fasting period.
The researchers of this study hypothesized that glycogen levels, the body’s way of storing sugar, decrease after time-restricted eating. They suggested that low glucose may improve insulin sensitivity due to an increased need to replenish glycogen stores.
They also wanted to investigate whether a 10-hour eating window would improve metabolism in overweight and obese people with type 2 diabetes aged 50 to 70 years.
To test this hypothesis, the researchers divided the participants into two groups: The first group restricted their eating time to a 10-hour window, while the placebo group was restricted to at least 14 hours for three weeks.
They observed a 4-week “washout period” before the researchers switched groups and repeated the experiment. This means that each participant “had their own control,” explained author Charlotte Andriessen, Ph.D. Student at Maastricht University, Netherlands, working in research MNT.
As part of the trial, researchers fitted participants with a glucose monitor that measured blood glucose every 15 minutes for both of the three-week trial periods. They also measured their glycogen stores during each phase of the experiment. Finally, they measured participants’ body composition and energy expenditure during a 36-hour breathing chamber at the clinic.
The researchers found that liver glycogen stores did not decrease after the time-restricted diet. However, they note that it was not measured during the night when people were fasting.
However, they found that total time in the healthy glycemic range increased by about 3 hours per day, and fasting glucose was lower when participants restricted their eating to a 10-hour window.
The study did not account for the potential effects of some participants’ glucose-lowering medications. The group was also small and included older participants, so the results may not be generalizable to the wider population.
“A younger group of volunteers may be more sensitive to a time-restricted feeding regimen because aging reduces insulin sensitivity and mitochondrial function, both of which are important in preventing greater use of glucose for energy throughout the day. fats at night,” Andriessen said.
“The main reason we included more postmenopausal women than premenopausal women is because of the hormonal changes that occur during menstruation,” she said.
The results, Andreessen said, may not be generalizable to people with prediabetes, who also benefit from a more time-restricted diet.
The authors behind the study say larger studies are needed to look at a 10-hour limited eating window.